Which option accurately describes the primary mechanism of action of acetaminophen?

• A. Inhibition of peripheral COX-2 blockade producing anti-inflammatory effects.
• B. Activation of mu opioid receptors to reduce pain.
• C. Central inhibition of prostaglandin synthesis (COX) in the CNS leading to analgesic and antipyretic effects, with minimal anti-inflammatory action.
• D. Blocking histamine release to reduce inflammation.

Answer: (C)